Am J Med. Jan;76(1) Severe allopurinol toxicity. Description and guidelines for prevention in patients with renal insufficiency. Hande KR, Noone RM. For more information, search the NLM HSDB database. Human Health Effects: Human Toxicity Excerpts: /SIGNS AND SYMPTOMS/ Allopurinol should be. Insights Into the Poor Prognosis of Allopurinol-Induced Severe Cutaneous Adverse Reactions: The Impact of Renal Insufficiency, High Plasma Levels of Oxypurinol and Granulysin. Of the patients with skin reactions, 26 had Stevens-Johnson syndrome (SJS), and 22 had drug rash with.
A life-threatening toxicity syndrome consisting of an erythematous, desquamative skin rash, fever, hepatitis, eosinophilia, and worsening renal function in Allopurinol, sold under the brand name Zyloprim among others, is a medication used to decrease high blood uric acid levels. It is specifically used to prevent. Allopurinol is a drug used to decrease the production of uric acid in the body. Skin rash is one of the most common adverse effects of Allopurinol in toxicity; it's.
Allopurinol - Get up-to-date information on Allopurinol side effects, uses, If you take too much too much allopurinol, call your local Poison. The reports that the concomitant use of ZYLOPRIM (allopurinol) and thi-azide diuretics may contribute to the enhancement of allopuri-nol toxicity in some. Summary for UKPID Allopurinol Kathryn Pughe, BSc (Hons) MRPharmS National Poisons Information Service (Newcastle Centre) Regional Drug. Allopurinol (Zyloprim) is used for treating gout, high levels of uric acid in the If you suspect an overdose, call or contact a poison control.